Cancers and tumors of the appendix are extremely rare, with an estimated incidence of 0.15 to 0.9 per 100,000 people. The average age of onset is between 50 and 55 years, and the disease appears to affect men and women equally.1 Evidence suggests that the incidence of appendix cancer has increased over the past 2 decades.2
There are different types of tumors that can originate in the appendix, including neuroendocrine tumors, appendiceal mucoceles, colonic-type adenocarcinoma, signet-ring cell adenocarcinoma, goblet cell carcinomas/adenoneuroendocrines, and paraganglioma.2
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